by Magdalena Nauerth | Nov 27, 2025 | News
The DFG has approved another funding period for LETSimmun! We are delighted to be able to continue our successful projects and to welcome new outstanding scientists and projects to our network.
by Magdalena Nauerth | Oct 26, 2023 | News
Interleukins are secreted proteins that regulate immune responses. Among these, the interleukin 12 (IL-12) family holds a central position in inflammatory and infectious diseases. Each family member consists of an α and a β subunit that together form a composite...
by Magdalena Nauerth | Sep 28, 2023 | News
Abstract Interleukin 12 (IL-12) plays major roles in immune defense against intracellular pathogens. By activating T cells and increasing antigen presentation, it is also a very potent anti-tumor molecule. Strong immune activation and systemic toxicity, however, so...
by Magdalena Nauerth | Apr 27, 2023 | News
Although CD19-directed chimeric antigen receptor T-cell therapy (CD19.CAR-T) has proven clinical efficacy for multiple refractory B-cell malignancies, over 50% of patients ultimately relapse. Recent evidence has underlined the critical role of the host in determining...
by Magdalena Nauerth | Oct 4, 2022 | News
MYB orchestrates T cell exhaustion and response to checkpoint inhibition Veit Buchholz and collegues have discovered a new populaation of T cells crucial for immunotherapy. This memory T cell subset is critical in maintaining the immune response against chronic...
