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Kruse, B., Buzzai, A. C., Shridhar, N., Braun, A. D., Gellert, S., Knauth, K., Pozniak, J., Peters, J., Dittmann, P., Mengoni, M., van der Sluis, T. C., Höhn, S., Antoranz, A., Krone, A., Fu, Y., Yu, D., Essand, M., Geffers, R., Mougiakakos, D., Kahlfuß, S., …, Kastenmüller, W.,… Tüting, T. (2023). CD4+ T cell-induced inflammatory cell death controls immune-evasive tumours. Nature, 10.1038/s41586-023-06199-x. Advance online publication. https://doi.org/10.1038/s41586-023-06199-x (B06)

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Nixdorf, D., Sponheimer, M., Berghammer, D., Engert, F., Bader, U., Philipp, N., Kazerani, M., Straub, T., Rohrbacher, L., Wange, L., Dapa, S., Atar, D., Seitz, C. M., Brandstetter, K., Linder, A., von Bergwelt, M., Leonhardt, H., Mittelstaet, J., Kaiser, A., Bücklein, V., … Subklewe, M. (2023). Adapter CAR T cells to counteract T-cell exhaustion and enable flexible targeting in AML. Leukemia, 37(6), 1298–1310. https://doi.org/10.1038/s41375-023-01905-0 (B01)

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Dötsch, S., Svec, M., Schober, K., Hammel, M., Wanisch, A., Gökmen, F., Jarosch, S., Warmuth, L., Barton, J., Cicin-Sain, L., D’Ippolito, E., & Busch, D. H. (2023). Long-term persistence and functionality of adoptively transferred antigen-specific T cells with genetically ablated PD-1 expression. Proceedings of the National Academy of Sciences of the United States of America, 120(10), e2200626120. https://doi.org/10.1073/pnas.2200626120 (A01)

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Rejeski, K., Cordas Dos Santos, D. M., Parker, N. H., Bücklein, V. L., Winkelmann, M., Jhaveri, K. S., Liu, L., Trinkner, P., Günther, S., Karschnia, P., Blumenberg, V., Schmidt, C., Kunz, W. G., von Bergwelt-Baildon, M., Jain, M. D., Theurich, S., & Subklewe, M. (2023). Influence of Adipose Tissue Distribution, Sarcopenia, and Nutritional Status on Clinical Outcomes After CD19 CAR T-cell Therapy. Cancer immunology research, 11(6), 707–719. https://doi.org/10.1158/2326-6066.CIR-22-0487 (B01, C05)

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Kuhl, N., Linder, A., Philipp, N., Nixdorf, D., Fischer, H., Veth, S., Kuut, G., Xu, T. T., Theurich, S., Carell, T., Subklewe, M., & Hornung, V. (2023). STING agonism turns human T cells into interferon-producing cells but impedes their functionality. EMBO reports, 24(3), e55536. https://doi.org/10.15252/embr.202255536 (B01, C03, C05)

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Pachmayr, L. O., Muehlbauer, A., Flommersfeld, S., Graml, F., Hoenninger, J., von Baumgarten, L., Buchholz, V. R., & Grassmann, S. (2023). Unbiased chemokine receptor screening reveals similar efficacy of lymph node- and tumor-targeted T cell immunotherapy. Cancer immunology, immunotherapy : CII, 10.1007/s00262-023-03472-w. Advance online publication. https://doi.org/10.1007/s00262-023-03472-w (B02)

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Seifert, M., Benmebarek, M. R., Briukhovetska, D., Märkl, F., Dörr, J., Cadilha, B. L., Jobst, J., Stock, S., Andreu-Sanz, D., Lorenzini, T., Grünmeier, R., Oner, A., Obeck, H., Majed, L., Dhoqina, D., Feinendegen, M., Gottschlich, A., Zhang, J., Schindler, U., Endres, S., … Kobold, S. (2022). Impact of the selective A2AR and A2BR dual antagonist AB928/etrumadenant on CAR T cell function. British journal of cancer, 127(12), 2175–2185. https://doi.org/10.1038/s41416-022-02013-z (B01)

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Mateyka, L. M., Strobl, P. M., Jarosch, S., Scheu, S. J. C., Busch, D. H., & D’Ippolito, E. (2022). Gene Signatures of T-Cell Activation Can Serve as Predictors of Functionality for SARS-CoV-2-Specific T-Cell Receptors. Vaccines, 10(10), 1617. https://doi.org/10.3390/vaccines10101617 (A01)

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Groll, T., Silva, M., Sarker, R. S. J., Tschurtschenthaler, M., Schnalzger, T., Mogler, C., Denk, D., Schölch, S., Schraml, B. U., Ruland, J., Rad, R., Saur, D., Weichert, W., Jesinghaus, M., Matiasek, K., & Steiger, K. (2022). Comparative Study of the Role of Interepithelial Mucosal Mast Cells in the Context of Intestinal Adenoma-Carcinoma Progression. Cancers, 14(9), 2248. https://doi.org/10.3390/cancers14092248 (C01)

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Dos Santos, D. M. C., Rejeski, K., Winkelmann, M., Liu, L., Trinkner, P., Günther, S., Bücklein, V. L., Blumenberg, V., Schmidt, C., Kunz, W. G., Von Bergwelt-Baildon, M., Theurich, S., & Subklewe, M. (2022). Increased visceral fat distribution and body composition impact cytokine release syndrome onset and severity after CD19 chimeric antigen receptor T-cell therapy in advanced B-cell malignancies. Haematologica, 107(9), 2096–2107. https://doi.org/10.3324/haematol.2021.280189 (B01, C05)

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Gosmann, D., Russelli, L., Weber, W. A., Schwaiger, M., Krackhardt, A. M., & D’Alessandria, C. (2022). Promise and challenges of clinical non-invasive T-cell tracking in the era of cancer immunotherapy. EJNMMI research, 12(1), 5. https://doi.org/10.1186/s13550-022-00877-z (A03)

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Kaeuferle, T., Stief, T. A., Canzar, S., Kutlu, N. N., Willier, S., Stenger, D., Ferrada-Ernst, P., Habjan, N., Peters, A. E., Busch, D. H., & Feuchtinger, T. (2022). Genome-wide off-target analyses of CRISPR/Cas9-mediated T-cell receptor engineering in primary human T cells. Clinical & translational immunology, 11(1), e1372. https://doi.org/10.1002/cti2.1372 (A01, B04, Z03)

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Wagner, K. I., Mateyka, L. M., Jarosch, S., Grass, V., Weber, S., Schober, K., Hammel, M., Burrell, T., Kalali, B., Poppert, H., Beyer, H., Schambeck, S., Holdenrieder, S., Strötges-Achatz, A., Haselmann, V., Neumaier, M., Erber, J., Priller, A., Yazici, S., Roggendorf, H., Protzer, U… Busch, D. H. (2022). Recruitment of highly cytotoxic CD8+ T cell receptors in mild SARS-CoV-2 infection. Cell reports, 38(2), 110214. https://doi.org/10.1016/j.celrep.2021.110214 (A01, B07)

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Albanese, M., Ruhle, A., Mittermaier, J., Mejías-Pérez, E., Gapp, M., Linder, A., Schmacke, N. A., Hofmann, K., Hennrich, A. A., Levy, D. N., Humpe, A., Conzelmann, K. K., Hornung, V., Fackler, O. T., & Keppler, O. T. (2022). Rapid, efficient and activation-neutral gene editing of polyclonal primary human resting CD4+ T cells allows complex functional analyses. Nature methods, 19(1), 81–89. https://doi.org/10.1038/s41592-021-01328-8(C03

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Schreiber, S., Honz, M., Mamozai, W., Kurktschiev, P., Schiemann, M., Witter, K., Moore, E., Zielinski, C., Sette, A., Protzer, U., & Wisskirchen, K. (2021). Characterization of a library of 20 HBV-specific MHC class II-restricted T cell receptors. Molecular therapy. Methods & clinical development, 23, 476–489. https://doi.org/10.1016/j.omtm.2021.10.012 (B07)

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Wu, H., Brand, B., Eckstein, M., Hochrein, S. M., Shumanska, M., Dudek, J., Nickel, A., Maack, C., Bogeski, I., & Vaeth, M. (2021). Genetic Ablation of the Mitochondrial Calcium Uniporter (MCU) Does not Impair T Cell-Mediated Immunity In Vivo. Frontiers in pharmacology, 12, 734078. https://doi.org/10.3389/fphar.2021.734078 (C05)

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Bashiri Dezfouli, A., Yazdi, M., Pockley, A. G., Khosravi, M., Kobold, S., Wagner, E., & Multhoff, G. (2021). NK Cells Armed with Chimeric Antigen Receptors (CAR): Roadblocks to Successful Development. Cells, 10(12), 3390. https://doi.org/10.3390/cells10123390 (B01)

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Zhang, W., Karschnia, P., von Mücke-Heim, I. A., Mulazzani, M., Zhou, X., Blobner, J., Mueller, N., Teske, N., Dede, S., Xu, T., Thon, N., Ishikawa-Ankerhold, H., Straube, A., Tonn, J. C., & von Baumgarten, L. (2021). In vivo two-photon characterization of tumor-associated macrophages and microglia (TAM/M) and CX3CR1 during different steps of brain metastasis formation from lung cancer. Neoplasia (New York, N.Y.), 23(11), 1089–1100. https://doi.org/10.1016/j.neo.2021.09.001 (B02)

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Altstetter, S. M., Quitt, O., Pinci, F., Hornung, V., Lucko, A. M., Wisskirchen, K., Jung, S., & Protzer, U. (2021). Hepatitis-D Virus Infection Is Not Impaired by Innate Immunity but Increases Cytotoxic T-Cell Activity. Cells, 10(11), 3253. https://doi.org/10.3390/cells10113253 (B07, C03)

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Bräunlein, E., Lupoli, G., Füchsl, F., Abualrous, E. T., de Andrade Krätzig, N., Gosmann, D., Wietbrock, L., Lange, S., Engleitner, T., Lan, H., Audehm, S., Effenberger, M., Boxberg, M., Steiger, K., Chang, Y., Yu, K., Atay, C., Bassermann, F., Weichert, W., Busch, D. H., … Krackhardt, A. M. (2021). Functional analysis of peripheral and intratumoral neoantigen-specific TCRs identified in a patient with melanoma. Journal for immunotherapy of cancer, 9(9), e002754. https://doi.org/10.1136/jitc-2021-002754 (A01, A03)

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Müller, T. R., Jarosch, S., Hammel, M., Leube, J., Grassmann, S., Bernard, B., Effenberger, M., Andrä, I., Chaudhry, M. Z., Käuferle, T., Malo, A., Cicin-Sain, L., Steinberger, P., Feuchtinger, T., Protzer, U., Schumann, K., Neuenhahn, M., Schober, K., & Busch, D. H. (2021). Targeted T cell receptor gene editing provides predictable T cell product function for immunotherapy. Cell reports. Medicine, 2(8), 100374. https://doi.org/10.1016/j.xcrm.2021.100374 (A01, B04, B07)

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Breidenbach M, Bader P, Attarbaschi A, Rossig C, Meisel R, Metzler M, Subklewe M, Mueller F, Schlegel PG, Teichert von Lüttichau I, Bourquin JP, Escherich G, Cario G, Lang P, Coffey R, von Stackelberg A, Willier S, Strahm B, Peters C, Feuchtinger T. (2025) Multinational retrospective analysis of bridging therapy prior to chimeric antigen receptor t cells for relapsed/refractory acute lymphoblastic leukemia in children and young adults.

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Wan, XS; Wisskirchen, K; Jin, T; Yang, L; Wang, XR; Wu, XA; Liu, F; Wu, Y; Ma, C; Pang, Y; Li, Q; Zhang, K; Protzer, U; Du, SD (2024) Genetically-modified, redirected T cells target hepatitis B surface antigen-positive hepatocytes and hepatocellular carcinoma lesions in a clinical setting

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Curion, F; Theis, FJ (2024) Machine learning integrative approaches to advance computational immunology

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Xie, Z; Protzer, U (2024) Activating adaptive immunity by bispecific, T-cell engager antibodies bridging infected and immune-effector cells is a promising novel therapy for chronic hepatitis B

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Svec, M; Dötsch, S; Warmuth, L; Trebo, M; Frässle, S; Riddell, SR; Jäger, U; D’Ippolito, E; Busch, DH (2024) A chimeric antigen receptor-based cellular safeguard mechanism for selective in vivo depletion of engineered T cells

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Schreiber, S; Dressler, LS; Loffredo-Verde, E; Asen, T; Färber, S; Wang, WS; Groll, T; Chakraborty, A; Kolbe, F; Kreer, C; Kosinska, AD; Simon, S; Urban, S; Klein, F; Riddell, SR; Protzer, U (2024) CARs derived from broadly neutralizing, human monoclonal antibodies identified by single B cell sorting target hepatitis B virus-positive cells

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Winterhalter, PM; Warmuth, L; Hilgendorf, P; Schütz, JM; Dötsch, S; Tonn, T; Cicin-Sain, L; Busch, DH; Schober, K (2024) HLA reduction of human T cells facilitates generation of immunologically multicompatible cellular products

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Maulana, TI; Teufel, C; Cipriano, M; Roosz, J; Lazarevski, L; van den Hil, FE; Scheller, L; Orlova, V; Koch, A; Hudecek, M; Alb, M; Loskill, P (2024) Breast cancer-on-chip for patient-specific efficacy and safety testing of CAR-T cells

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Curion, F; Rich-Griffin, C; Agarwal, D; Ouologuem, S; Rue-Albrecht, K; May, L; Garcia, GEL; Heumos, L; Thomas, T; Lason, W; Sims, D; Theis, FJ; Dendrou, CA (2024) Panpipes: a pipeline for multiomic single-cell and spatial transcriptomic data analysis

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Mühlgrabner, V; Peters, T; Cárdenas, RMHV; Salzer, B; Göhring, J; Plach, A; Höhrhan, M; Perez, ID; Goncalves, VD; Farfán, JS; Lehner, M; Stockinger, H; Schamel, WW; Schober, K; Busch, DH; Hudecek, M; Dushek, O; Minguet, S; Platzer, R; Huppa, JB (2024) TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation

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Maerkl, F; Schultheiss, C; Ali, M; Chen, SS; Zintchenko, M; Egli, L; Mietz, J; Chijioke, O; Paschold, L; Spajic, S; Holtermann, A; Doerr, J; Stock, S; Zingg, A; Laeubli, H; Piseddu, I; Anz, D; Minden, MDV; Zhang, TJ; Nerreter, T; Hudecek, M; Minguet, S; Chiorazzi, N; Kobold, S; Binder, M. (2024) Mutation-specific CAR T cells as precision therapy for IGLV3-21R110 expressing high-risk chronic lymphocytic leukemia

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Cai, C; Keoshkerian, E; Wing, K; Samir, J; Effenberger, M; Schober, K; Bull, RA; Lloyd, AR; Busch, DH; Luciani, F. (2024) Discovery of a monoclonal, high-affinity CD8+ T-cell clone following natural hepatitis C virus infection

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Thiel, U; von Heyking, K; Xue, BS; Gassmann, H; Thiede, M; Schober, K; Mautner, J; Hauer, J; Ruland, J; Busch, DH; Burdach, SEG (2024) T CELLS DIRECTED AGAINST THE METASTATIC DRIVER CHONDROMODULIN-1 IN EWING SARCOMA: COMPARATIVE ENGINEERING WITH CRISPR/CAS9 VS. RETROVIRAL GENE TRANSFER FOR ADOPTIVE TRANSFER

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Negraschusl, A; Holtermann, A; Edelmann, S; Rupp, L; Füchsl, F; Krackhardt, A; Schmitz, M; Kobold, S; Heissmeyer, V. (2024) MALT1-induced Roquin cleavage in T cells and CAR T cells is critical for anti-tumor immunity

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Ursch, LT; Müschen, JS; Ritter, J; Klermund, J; Bernard, BE; Kolb, S; Warmuth, L; Andrieux, G; Miller, G; Jiménez-Muñoz, M; Theis, FJ; Boerries, M; Busch, DH; Cathomen, T; Schumann, K. (2024) Modulation of TCR stimulation and pifithrin-a improve the genomic safety profile of CRISPR-engineered human T cells

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Xhaxho, S; Chen-Wichmann, L; Kreissig, S; Windisch, R; Gottschlich, A; Nandi, S; Schabernack, S; Kohler, I; Kellner, C; Kobold, S; Humpe, A; Wichmann, C. (2024) Efficient Chimeric Antigen Receptor T-Cell Generation Starting with Leukoreduction System Chambers of Thrombocyte Apheresis Sets

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Pekayvaz, K; Losert, C; Knottenberg, V; Gold, C; van Blokland, IV; Oelen, R; Groot, HE; Benjamins, JW; Brambs, S; Kaiser, R; Gottschlich, A; Hoffmann, GV; Eivers, L; Martinez-Navarro, A; Bruns, N; Stiller, S; Akgoel, S; Yue, KY; Polewka, V; Escaig, R; Joppich, M; Janjic, A; Popp, O; Kobold, S; Petzold, T; Zimmer, R; Enard, W; Saar, K; Mertins, P; Huebner, N; van der Harst, P; Franke, LH; van der Wijst, MGP; Massberg, S; Heinig, M; Nicolai, L; Stark, K. (2024) Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes

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Holtermann, A; Gislon, M; Angele, M; Subklewe, M; von Bergwelt-Baildon, M; Lauber, K; Kobold, S (2024) Prospects of Synergy: Local Interventions and CAR T Cell Therapy in Solid Tumors

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Hiltensperger, M; Ruland, J; Schober, K. (2024) Harnessing naturally occurring mutations for T-cell therapy: a potential new avenue to enhance treatment efficacy

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Isay, SE; Vornholz, L; Schnalzger, T; Groll, T; Magg, T; Loll, P; Weirich, G; Steiger, K; Hauck, F; Ruland, J. (2024) Enforced CARD11/MALT 1 signaling in dendritic cells triggers hemophagocytic lymphohistioc

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Trefny, MP; Kobold, S. (2024) CAR T cells for solid tumors – developments to watch in 2023

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Caulier, B; Joaquina, S; Gelebart, P; Dowling, TH; Kaveh, F; Thomas, M; Tandaric, L; Wernhoff, P; Katyayini, NU; Wogsland, C; Gjerstad, ME; Floisand, Y; Kvalheim, G; Marr, C; Kobold, S; Enserink, JM; Gjertsen, BT; McCormack, E; Inderberg, EM; Wälchli, S. (2024) CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia

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Nowotny, HF; Zheng, TT; Seiter, TM; Ju, J; Schneider, H; Kroiss, M; Sarkis, AL; Sturm, L; Britz, V; Lechner, A; Potzel, AL; Kunz, S; Bidlingmaier, M; Neuhaus, K; Gottschlich, A; Kobold, S; Reisch, N; Schirmer, M; Reincke, M; Adolf, C. (2024) Sex-dependent modulation of T and NK cells and gut microbiome by low sodium diet in patients with primary aldosteronism

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Nguyen, NTT; Müller, R; Briukhovetska, D; Weber, J; Feucht, J; Künkele, A; Hudecek, M; Kobold, S. (2024) The Spectrum of CAR Cellular Effectors: Modes of Action in Anti-Tumor Immunity

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fzali, AM; Nirschl, L; Sie, C; Pfaller, M; Ulianov, O; Hassler, T; Federle, C; Petrozziello, E; Kalluri, SR; Chen, HH; Tyystjärvi, S; Muschaweckh, A; Lammens, K; Delbridge, C; Büttner, A; Steiger, K; Seyhan, G; Ottersen, OP; Öllinger, R; Rad, R; Jarosch, S; Straub, A; Mühlbauer, A; Grassmann, S; Hemmer, B; Böttcher, JP; Wagner, I; Kreutzfeldt, M; Merkler, D; Pardàs, IB; Schmidt Supprian, M; Buchholz, VR; Heink, S; Busch, DH; Klein, L; Korn, T. (2024) B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4

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Xu, M; Ito-Kureha, T; Kang, HS; Chernev, A; Raj, T; Hoefig, KP; Hohn, C; Giesert, F; Wang, YH; Pan, WL; Zietara, N; Straub, T; Feederle, R; Daniel, C; Adler, B; König, J; Feske, S; Tsokos, GC; Wurst, W; Urlaub, H; Sattler, M; Kisielow, J; Wulczyn, FG; Lyszkiewicz, M; Heissmeyer, V. (2024) The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3′-UTR and promoting Rag1 mRNA expression

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Rasche, L; Hudecek, M; Einsele, H. CAR T-cell therapy in multiple myeloma: mission accomplished?

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Blobner, J; Dengler, L; Eberle, C; Herold, JJ; Xu, T; Beck, A; Mühlbauer, A; Müller, KJ; Teske, N; Karschnia, P; van den Heuvel, D; Schallerer, F; Ishikawa-Ankerhold, H; Thon, N; Tonn, JC; Subklewe, M; Kobold, S; Harter, PN; Buchholz, VR; von Baumgarten, L. (2024) PD-1 blockade does not improve efficacy of EpCAM-directed CAR T-cell in lung cancer brain metastasis

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Gehrke, L; Gonçalves, VD; Andrae, D; Rasko, T; Ho, P; Einsele, H; Hudecek, M; Friedel, SR. (2024) Current Non-Viral-Based Strategies to Manufacture CAR-T Cells

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Hänel, G; Schönle, A; Neumann, AS; Nixdorf, D; Philipp, N; Sponheimer, M; Leutbecher, A; Emhardt, AJ; Magno, G; Bücklein, V; Eckmann, J; Dunshee, D; Kramar, V; Korfi, K; Colombetti, S; Umaña, P; Klein, C; Subklewe, M. (2024) Combining venetoclax and azacytidine with T-cell bispecific antibodies for treatment of acute myeloid leukemia: a preclinical assessment

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Nair, R; Salinas-Illarena, A; Sponheimer, M; Wullkopf, I; Schreiber, Y; Corte-Real, JV; Ben, AD; Marterer, H; Thomas, D; Geisslinger, G; Cinatl, J; Subklewe, M; Baldauf, HM (2024) Novel Vpx virus-like particles to improve cytarabine treatment response against acute myeloid leukemia

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Kazerani, M; Marcinek, A; Philipp, N; Brauchle, B; Taylor, JJ; Moreno, HD; Terrasi, A; Tast, B; Rohrbacher, L; Wang, YS; Warm, M; Emhardt, AJ; Magno, G; Spiekermann, K; Herold, T; Straub, T; Theurich, S; Schotta, G; Kischel, R; Bücklein, VL; Subklewe, M. (2024) Evolution of T-cell fitness through AML progression: enhanced bispecific T-cell engager-mediated function of bone marrow T cells at remission compared to initial diagnosis and relapse

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Vera-Cruz, S; Culubret, MJ; Konetzki, V; Alb, M; Friedel, SR; Hudecek, M; Einsele, H; Danhof, S; Scheller, L. (2024) Cellular Therapies for Multiple Myeloma: Engineering Hope

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dos Santos, DMC; Tix, T; Shouval, R; Gafter-Gvili, A; Alberge, JB; Cliff, ERS; Theurich, S; von Bergwelt-Baildon, M; Ghobrial, IM; Subklewe, M; Perales, MA; Rejeski, K. (2024) A systematic review and meta-analysis of nonrelapse mortality after CAR T cell therapy

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Vinnakota, JM; Biavasco, F; Schwabenland, M; Chhatbar, C; Adams, RC; Erny, D; Duquesne, S; El Khawanky, N; Schmidt, D; Fetsch, V; Zaehringer, A; Salie, H; Athanassopoulos, D; Braun, L; Javorniczky, NR; Ho, JNHG; Kierdorf, K; Marks, R; Waesch, R; Simonetta, F; Andrieux, G; Pfeifer, D; Monaco, G; Capitini, C; Fry, TJ; Blank, T; Blazar, B; Wagner, E; Theobald, M; Sommer, C; Stelljes, M; Reicherts, C; Jeibmann, A; Schittenhelm, J; Monoranu, CM; Rosenwald, A; Kortuem, M; Rasche, L; Einsele, H; Meyer, PT; Brumberg, J; Voelkl, S; Mackensen, A; Coras, R; von Bergwelt-Baildon, M; Albert, NL; Bartos, LM; Brendel, M; Holzgreve, A; Mack, M; Boerries, M; Mackall, CL; Duyster, J; Henneke, P; Priller, J; Koehler, N; Struebing, F; Bengsch, B; Ruella, M; Subklewe, M; von Baumgarten, L; Gill, S; Prinz, M; Zeiser, R. (2024) Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome

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Rejeski, K; Jain, M; Shah, NN; Perales, MA; Subklewe, M. (2024) Immune effector cell-associated haematotoxicity after CAR T-cell therapy: from mechanism to management

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Torcellan, T; Friedrich, C; Doucet-Ladeveze, R; Ossner, T; Sole, VV; Riedmann, S; Ugur, M; Imdahl, F; Rosshart, SP; Arnold, SJ; Aguero, MGD; Gagliani, N; Flavell, RA; Backes, S; Kastenmuller, W; Gasteiger, G. (2024) Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection

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Chang, YS; Bach, L; Hasiuk, M; Wen, LF; Elmzzahi, T; Tsui, C; Gutiérrez-Melo, N; Steffen, T; Utzschneider, DT; Raj, T; Jost, PJ; Heink, S; Cheng, JY; Burton, OT; Zeiträg, J; Alterauge, D; Dahlström, F; Becker, JC; Kastl, M; Symeonidis, K; van Uelft, M; Becker, M; Reschke, S; Krebs, S; Blum, H; Abdullah, Z; Paeschke, K; Ohnmacht, C; Neumann, C; Liston, A; Meissner, F; Korn, T; Hasenauer, J; Heissmeyer, V; Beyer, M; Kallies, A; Jeker, LT; Baumjohann, D. (2024) TGF-β specifies TFH versus TH17 cell fates in murine CD4+ T cells through c-Maf

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Scheller, L; Tebuka, E; Rambau, PF; Einsele, H; Hudecek, M; Prommersberger, SR; Danhof, S. (2024) BCMA CAR-T cells in multiple myeloma-ready for take-off?

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Breidenbach, M; Bader, P; Attarbaschi, A; Rossig, C; Meisel, R; Metzler, M; Subklewe, M; Mueller, F; Schlegel, PG; von Lüttichau, IT; Bourquin, JP; Escherich, G; Cario, G; Lang, PT; Coffey, R; von Stackelberg, A; Willier, S; Strahm, B; Peters, C; Feuchtinger, T (2025) Multinational retrospective analysis of bridging therapy prior to chimeric antigen receptor t cells for relapsed/refractory acute lymphoblastic leukemia in children and young adults

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Grunewald, L; Andersch, L; Helmsauer, K; Schwiebert, S; Klaus, A; Henssen, AG; Straka, T; Lodrini, M; Wicha, SG; Fuchs, S; Hertwig, F; Westermann, F; Vitali, A; Caramel, C; Büchel, G; Eilers, M; Astrahantseff, K; Eggert, A; Höpken, UE; Schulte, JH; Blankenstein, T; Anders, K; Künkele, A. (2025)Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy

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Stock, S; Bücklein, VL; Blumenberg, V; Magno, G; Emhardt, AJ; Holzem, AME; dos Santos, DMC; Schmidt, C; Griesshammer, S; Frölich, L; Kobold, S; von Bergwelt-Baildon, M; Rejeski, K; Subklewe, M (2025) Prognostic significance of immune reconstitution following CD19 CAR T-cell therapy for relapsed/refractory B-cell lymphoma

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Schwarzlmueller, P; Triebig, A; Assié, G; Jouinot, A; Theurich, S; Maier, T; Beuschlein, F; Kobold, S; Kroiss, M. (2025) Steroid hormones as modulators of anti-tumoural immunity

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Walter, JD; Beffinger, M; Egloff, P; Zimmermann, I; Hürlimann, LM; Ackle, F; Seifert, M; Kobold, S; vom Berg, J; Seeger, MA. (2025) Flycodes enable simultaneous preclinical analysis for dozens of antibodies in single cassette-dosed mice

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Gottschlich, A; Grünmeier, R; Hoffmann, GV; Nandi, S; Kavaka, V; Müller, PJ; Jobst, J; Oner, A; Kaiser, R; Gärtig, J; Piseddu, I; Frenz-Wiessner, S; Fairley, SD; Schulz, H; Igl, V; Janert, TA; Di Fina, L; Mulkers, M; Thomas, M; Briukhovetska, D; Simnica, D; Carlini, E; Tsiverioti, CA; Trefny, MP; Lorenzini, T; Märkl, F; Mesquita, P; Brabenec, R; Strzalkowski, T; Stock, S; Michaelides, S; Hellmuth, J; Thelen, M; Reinke, S; Klapper, W; Gelebart, PF; Nicolai, L; Marr, C; Beltrán, E; Megens, RTA; Klein, C; Baran-Marszak, F; Rosenwald, A; von Bergwelt-Baildon, M; Bröckelmann, PJ; Endres, S; Kobold, S. (2025) Dissection of single-cell landscapes for the development of chimeric antigen receptor T cells in Hodgkin lymphoma

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Peter, J; Toppeta, F; Trubert, A; Danhof, S; Hudecek, M; Däullary, T. (2025) Multi-Targeting CAR-T Cell Strategies to Overcome Immune Evasion in Lymphoid and Myeloid Malignancies

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Schütz, B; Krause, FF; Taudte, RV; Zaiss, MM; Luu, M; Visekruna, A. (2025) Modulation of Host Immunity by Microbiome-Derived Indole-3-Propionic Acid and Other Bacterial Metabolites

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Mestermann, K; Garitano-Trojaola, A; Hudecek, M. (2025) Accelerating CAR-T Cell Therapies with Small-Molecule Inhibitors

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Kobold, S. (2025) RORing CAR T Cells in Solid and Hematologic Cancers: Same but Different

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Lorenzini T, Cadilha BL, Obeck H, Benmebarek MR, Märkl F, Michaelides S, Strzalkowski T, Briukhovetska D, Müller PJ, Nandi S, Winter P, Majed L, Grünmeier R, Seifert M, Rausch S, Feuchtinger T, Endres S, Kobold S. (2025) Rational design of PD-1-CD28 immunostimulatory fusion proteins for CAR T cell therapy.

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Blaeschke F, Ortner E, Stenger D, Mahdawi J, Apfelbeck A, Habjan N, Weißer T, Kaeuferle T, Willier S, Kobold S, Feuchtinger T. (2025) Design and Evaluation of TIM-3-CD28 Checkpoint Fusion Proteins to Improve Anti-CD19 CAR T-Cell Function.