| A01 |

| A01 |

Title

Title

Orthotopic T cell receptor replacement by advanced non-viral cell engineering

| A02 |

| A02 |

Title

Title

Adapter CAR technologies to steer T cell function and track T cell fait through in vivo imaging with radioligands

| A03 |

| A03 |

Title

Title

Targeting neoantigens in multiple myeloma by TCR-transgenic T cells

|A04|

|A04|

Title

Title

Extending and controlling lymphocyte functionalities by engineering cytokines and their receptors

|A05|

|A05|

Title

Title

Super-resolution microscopy to visualize CAR- and recombinant TCR-T cell receptome and function

|A06|

|A06|

Title

Title

Engineering CAR-T cells against neuroblastoma with synthetic notch receptors to increase tumor-specificity and endogenous immune activation

|A07|

|A07|

Title

Title

Developing polyclonal TCR-T cell therapies using CRISPR base and prime editing

|A08|

|A08|

Title

Title

AI-powered chimeric receptors to overcome therapeutic resistance in myeloma

|B01|

|B01|

Title

Title

CAR T for treatment of acute myeloid leukemia (AML): Chemokine and cytokine targeted switch receptors

|B02|

|B02|

Title

Title

Novel strategies to enhance adoptive T cell therapy for intracranial pediatric solid tumors

 

|B03|

|B03|

Title

Title

Engineering CAR-NK cells for sustained tissue functionality

|B04|

|B04|

Title

Title

Tandem T cell engineering to overcome immune dysregulation induced by acute leukemia

|B05|

|B05|

Title

Title

Combining enhanced TCR- and CAR-transgenic T cell products targeting (neo)antigens in multiple myeloma

|B06|

|B06|

Title

Title

Universal CD4 helper CAR-T cells for cancer immunotherapy

|B07|

|B07|

Title

Title

Overcoming Barriers for T cell Therapy in the Liver for Hepatitis B and Hepatocellular Carcinoma (HCC)

 

|C01|

|C01|

Title

Title

Exploitation of negative regulators of TCR signaling for therapeutic lymphocyte engineering

|C02|

|C02|

Title

Title

Engineering of tumor antigen-specific CD8+ T cells with de novo protein design to modulate Roquin function

 

|C03|

|C03|

Title

Title

Harnessing STING signaling to enhance CAR-T cell therapy for solid tumors

|C04|

|C04|

Title

Title

Evaluating the therapeutic potential of genetically engineered CAR-Tregs for the treatment of inflammatory bowel disease

|Z01|

|Z01|

Title

Title

Central Tasks of the Collaborative Research Center

 

 

|Z02|

|Z02|

Title

Title

Bench-to-Bedside ATMP Development Platform

 

|Z03|

|Z03|

Title

Title

Integrative and immunoprofiling analysis for single-cell and spatial genomics

 

Contact Details

Coordination & project management
Dr. Magdalena Nauerth

Trogerstr.30
81675 München

+4989 4140 6887

Contact Form

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